Lab of Molecular Neuroscience -Furuichi Lab
A web site for alumni of the Furuichi Laboratory
古市研究室の同窓生のためのサイト
and the Laboratory for Molecular Neurogenesis, RIKEN Brain Science Institute (1999~2010)
東京理科大学理工学部応用生物科学科(2011~2020)と理研脳科学総合研究センター分子神経形成研究チーム(1999~2010)
Recent Achievements
We showed that CAPS2/Cadps2 deficiencies altered oxytocin release, resulting in impaired social behavior in mice.
Fujima S, Yamaga R, Minami H, Mizuno S, Shinoda Y, Sadakata T, Abe M, Sakimura K, Sano Y, and Furuichi T. CAPS2 deficiency impairs the release of the social peptide, oxytocin, as well as oxytocin-associated social behavior. Journal of Neuroscience. 41(20):4524-4535, 2021.
We showed that CAPS2/Cadps2 deficiencies in mice cause cytoplasmic accumulation of secretory granules (zymogen granules), decreased amylase secretion, and acinar cell injury in the exocrine pancreas.
Sato Y, Tsuyusaki M, Takahashi-Iwanaga H, Fujisawa R, Masamune A, Hamada S, Matsumoto R, Tanaka Y, Kakuta Y, Yamaguchi-Kabata Y, Furuse T, Wakana S, Shimura T, Kobayashi R, Shinoda Y, Goitsuka R, Maezawa S, Sadakata T, Sano Y, and Furuichi T. Loss of CAPS2/Cadps2 leads to exocrine pancreatic cell injury and intracellular accumulation of secretory granules in mice. Frontiers in Molecular Biosciences 9:1040237, 2022.
