CAPS2/Cadps2 is responsible for pancratic exocrine function (see "Read More" in the "Achievements" )

Loss of CAPS2/Cadps2 in mice causes chronic pancreatitis-like phenotype including excess cytoplasmic accmulation of secretory (zymogen) granules and their content amylase, decreased amylase secretion, aberrant intracellular membrane structures, acinar cell atrophy and apoptosis, fibrosis, and inflammation.

Sato Y, Tsuyusaki M, et al, Front. Mol. Biosicence, 2022 https://doi.org/10.3389/fmolb.2022.1040237